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SmartTRAK Life Sciences News and Analysis Blog

2 min read

Trends to Watch in 2025: Interventional Technologies Disrupting the Treatment of CLBP

By Kris Jacques on 4/29/25 9:30 AM

SmartTRAK discusses the latest technologies disrupting the standard of care for chronic low back pain (CLBP)

Non-surgical and less invasive treatment options for CLBP continue to evolve, closing the gap between conservative management and surgical intervention. SmartTRAK estimates that over 450K surgical procedures were performed for low back pain in the US in 2024. However, the number of patients suffering from CLBP is far more significant, and we estimate that over 11 million patients can be treated with new, non-surgical and less invasive technologies.

The treatment approach for spinal back pain starts with conservative measures and progresses to more invasive treatments, depending on the severity and nature of the pain. Treating patients earlier in the cascade can delay the progression and reduce the need for more costly care.
 
In this downloadable article, SmartTRAK discusses the companies and technologies advancing earlier intervention with the potential for disrupting the standard of care cascade, including non-surgical Intradiscal therapeutics and MIS restorative therapies. The article also covers the ongoing shift from spine surgeons to interventionists and the increasingly prominent role of interventional pain physicians. 
 
Click the button below to read the complete Market Outlook article "Trends to Watch in 2025: Interventional Technologies Disrupting the Treatment of CLBP" by Kris Jacques, SmartTRAK  Sr Analyst, Spine and Intradiscal Therapeutics.Get the Article
Topics: Spine
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3 min read

SentryX: Implantable Anesthetic for Spine Surgery

By Kris Jacques on 4/22/25 9:30 AM

SmartTRAK spotlights SentryX, a clinical-stage biopharmaceutical company developing a non-opioid platform for the treatment of acute pain after surgery,​ in an interview at AAOS 2025 in San Diego. 

SentryX Co-Founder and Chief Medical Officer Jorrit-Jan (JJ) Verlaan, MD, discusses the company’s novel implantable anesthetic for spine surgery applications in an interview with SmartTRAK at the American Academy of Orthopaedic Surgeons (AAOS) 2025 Annual meeting in San Diego. The hydrogel works with all types of small-molecule drugs with a release profile that can be tailored to specific clinical needs and surgical procedures.

To find out more about SentryX and its novel technology, listen to the following video. (13:37 min.) A link to download a transcript of the interview is also provided below.


Hi, I’m Kristine Jacques, a Senior Analyst with SmartTRAK Spine. We are here at the American Academy of Orthopedic Surgeons 2025. I’m sitting down with Dr. JJ Verlaan, a spine surgeon, co-founder, and Chief Medical Officer for SentryX, a Netherlands-based company developing a groundbreaking non-opioid solution for postoperative pain. First of all, Dr. Verlaan, I want to congratulate you on being one of the top four finalists inthe OrthoPitch Event at the Academy this year. It’s quite an honor.

Dr. Jorrit-Jan Verlaan: Thank you very much.

Thank you so much for sitting down with the SmartTRAK team. I’d like to start out with you telling us about your background and how the idea came about for the Hydrogel and starting SentryX.

JJV: Thank you so much. I'm a surgeon from Utrecht in the Netherlands. I've been practicing spine surgery from the moment I got board-certified. Rapidly, during work in my practice, I noticed that patients after spine surgery are all in a lot of pain. The moment that you realize that, and you actually ask the patients how much pain they have, on a scale of 0-10 they sometimes respond with a 12. I had a chat with an anesthesiologist one day in between surgeries. We were discussing what is out there right now to treat pain. The anesthesiologist, she told me, "Well, not much, really. We're still relying on opioids. Maybe we could do something with local anesthetics, but it's not working long enough at this point." That kind of sparked the idea of doing something locally to treat the pain, but differently. Soon after, I hit upon the idea that we're developing right now in the company.

How far along are you in the development?

JJV: We started in 2017, together with my partner Bas Oosterman who is the CEO of the company. First it was just a raw idea. We soon found out that this idea, it had never been done before. That gave us the opportunity to actually file IP on our solution and go for it. At the end of 2017  we officially founded the company. We got our first employees and collaborated with a renowned institute on biofabrication. We developed a new ...

Click the button below to download and read the complete transcript of SmartTRAK's interview with SentryX Co-Founder and CMO Jorrit-Jan (JJ) Verlaan, MD, conducted by Kris Jacques, SmartTRAK Sr Analyst.Download the Transcript

Topics: Spine
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2 min read

Spine Market Shake-Up: Trends, Drivers and What’s Next

By Elise Wolf on 3/18/25 9:30 AM

SmartTRAK delves into recent spinal implant divestitures.

The global Spinal Implant Market has seen an increasing number of divestitures in recent years. Large strategics are streamlining their portfolios, while private equity firms and specialized manufacturers are capitalizing on the opportunity to acquire divested assets. In this article, SmartTRAK explores the key drivers behind these divestitures, notable transactions and the broader implications for the industry, including:

  • Recent Divestitures from Key Players
    • In January, Stryker (SYK) announced a definitive agreement to sell its US spinal implants business to the Viscogliosi Brothers (VB), a New York-based investment firm focused on neuro and musculoskeletal technologies. VB Spine is set to become ... (read more)
  • Why the Shake-ups? 
    • The Spine Hardware Market is characterized as a very SKU-heavy business with little differentiation among implants, making it expensive and requiring savvy and specialized operations to ensure profitability. Market-leading strategics, Medtronic (MDT) and Globus (GMED) are acquiring ... (read more)
  • Focus on Interventional Market
    • With ZBH and SYK exiting the spinal fusion space altogether, other companies are targeting adjacent high-growth markets, where there is a much larger population of chronic low back pain (CLBP) patients to treat in lieu of fusion. Post divestiture, SYK will retain ... (read more)
  • Continued Evolution Expected
    • Consolidation and specialization in the Spine Market could lead to improved product quality, better integration of new technologies and enhanced patient outcomes. SmartTRAK expects the Spine Market 
      will ...(read more)

Curious about the latest transactions and trends in the Spine Market and the broader implications for the industry? Click the button below to download the complete market outlook article, "Spine Market Shake-Up: Trends, Drivers and What’s Next" by Elise Wolf, SmartTRAK VP& GM, Orthopedics & Quality.Get the Article


SmartTRAK is the Medtech industry’s only global Insights-as-a-Service solution for the Orthopedics, Wound Care, Regenerative Medicine and Neuro Therapy markets. SmartTRAK’s propriety methodology turns disparate data from hundreds of sources into powerful insights customers can rely on as the trusted source for strategic decision-making. The SmartTRAK enterprise platform includes rich daily updates, comprehensive market coverage and simple-to-use tools and dashboards for market, product and financial analysis. Customers leveraging the SmartTRAK platform also have direct access to market experts for inquiries and advisory services. If you would like a demo of what SmartTRAK has to offer and see how we can help increase proficiency, improve productivity and reduce costs for your company, just click here.
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3 min read

Musculoskeletal New Ventures Conference 2024

By Erin Dorgan on 12/3/24 9:40 AM

New spine technologies "pushed the envelope" at MNVC

The Musculoskeletal New Ventures Conference (MNVC) is an annual meeting where early and late-stage companies present their ideas. This meeting occurred in Memphis, Tennessee, from October 28 - 30, with a broad mix of attendees, including surgeons, venture capitalists, the medical device industry and researchers. Forty companies presented this year, a record number for this meeting, focused exclusively on the musculoskeletal industry. In this article, SmartTRAK highlights six companies with new technologies to "push the envelope" in the US Spinal Hardware Market, which SmartTRAK estimates is growing at a 5-year CAGR of +4.7%.

This downloadable article provides an in-depth look at the following six companies' innovative new technologies:

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3 min read

NASS 2024: Enabling Tech Still Making Waves

By Elise Wolf on 10/29/24 9:30 AM

Technological advances, new market entrants and novel technology continue to make waves at NASS 2024.

SmartTRAK attended this year’s 39th Annual North American Spine Society (NASS) meeting in Chicago, IL, which took place September 25-28, 2024. With the attendance of industry professionals rivaling that of surgeons at this year’s meeting, enabling technology continued to make waves on the exhibit floor yet again. The ongoing focus on enabling tech is not surprising given that robotics and navigation platforms have continued to support Spine Hardware Market growth in recent years. To date in 2024, SmartTRAK estimates that the Enabling Tech Market for Robotics and Navigation has increased at near double-digits (+9.6% growth) YoY through Q224, according to SmartTRAK Financial Dashboard

Among the many topics discussed in this article are:

  • Robot Wars Heating Up in Spine
    • Robotics were on display from market leaders Medtronic (MDT) and Globus Medical (GMED) at NASS 2024. MDT announced new advancements in its AiBLE ecosystem including ... (read more)
  • Augmented/Mixed Reality on Display
    • Augmented reality-based navigation solutions were also showcased at the meeting. At NASS 2024, SmartTRAK learned that the Augmedics xvision augmented-reality based intraoperative navigation system has been used to treat ... (read more)
  • Novel Handheld Navigation Designed to Overcome Challenges
    • In a NASS 2024 Symposium entitled “The Symbiosis of Robotics, Enabling Technology and Minimally Invasive Surgery,” panelists mentioned that one limitation of many robotic and navigation systems is ... (read more)
  • Ongoing Technological Advances
    • With increasing adoption of enabling technologies and a growing level of experience in using them in spine procedures comes a better understanding of the advantages and limitations of current assistive technology solutions. Companies across the industry from large strategics to small start-ups are continuing to make ... (read more)

Click the button below to download and read the complete "NASS 2024: Enabling Tech Still Making Waves" market perspective article by Elise Wolf, GM & VP, SmartTRAK Orthopedics & Quality.

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2 min read

NASS 2024: Highlights from the Annual Meeting in Chicago

By Erin Dorgan on 10/15/24 9:30 AM

New products and clinical data continue to grow the spinal hardware and bone replacement markets.

The North American Spine Society (NASS) was buzzing with new technologies at its 39th annual meeting in Chicago, September 25-28. Over 4,000 medical registrants and industry personnel attended this year’s meeting. This is the largest spine-focused meeting in the US, and it supports the spinal hardware and bone replacement markets. SmartTRAK estimates the spinal hardware market is poised to post a 5-yr CAGR of +4.7%, and the bone replacement market in spine is expected to reach a 5-year CAGR of +3.5%.

In this market perspective article, SmartTRAK highlights ...

  • Spine Hardware Refreshed-The Latest Product Innovations
    • Pedicle Screws
    • Disc Prep
  • Bone Replacement Market - New Products for DBM
    • The Data Race Continues
    • Product Innovations
  • A Strong Showing from Korean Manufacturers
    • New this year at NASS was the Korean SpineTech Pavilion, sponsored by the Korean Ministry of Health and Welfare and the Korean Health Industry Development Institute. This pavilion housed smaller companies at one booth to showcase ...

Click the button below to download and read the complete "NASS 2024 Annual Meeting Highlights" market perspective article by Erin Dorgan, SmartTRAK Senior Analyst, Spine.

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3 min read

SMISS 2024 - MIS Spine Continues to Grow

By Erin Dorgan on 10/8/24 9:28 AM

SmartTRAK takes a look at trends impacting the MIS Spine market.

The seventeenth Society of Minimally Invasive Spine Surgery (SMISS) Annual Forum was held in Las Vegas, Nevada, from September 5 to 7. It is the only US-based spine meeting dedicated to minimally invasive surgery (MIS). At this year’s meeting, the presenters focused on “innovate, adapt and evolve.”
 

In this article, SmartTRAK highlights key presentations and the latest trends from SMISS 2024 affecting the Spine Market. This includes what challenges still exist for MIS transforaminal lumbar interbody fusion (TLIF) procedures, considerations for surgeons learning the prone transpsoas (PTP) approach, indication expansion opportunities for cervical disc replacement (CDR) and factors that could disrupt the market for spine surgeons. SmartTRAK estimates these trends will contribute to the US MIS market 5-year CAGR of +7.0% by 2028. 

The topics covered include:

  • New Technologies Help Advance MIS TLIF Procedures
    • SmartTRAK estimates that MIS posterior procedures will reach 88K in 2028E, and over half of the interbody procedures are ... (read more)
  • Lateral Lumbar Interbody Procedures Growing in Mid-Single Digits
    • One of the fastest growing segments of the MIS Spine Market is Lateral Lumbar Interbody Fusion, which SmartTRAK estimates is growing with a 5-year CAGR of ... (read more)
  • Cervical Disc Replacement Indications Poised to Expand
    • SmartTRAK estimates that the CDR market is one of the fastest growth markets in Spine, with a projected 5-year revenue ... (read more)
  • ‘Innovator’s Dilemma’ Could Disrupt the Spine Market for Surgeons
    • Concluding the meeting with his presidential address, Sheeraz Qureshi, MD, MBA, Co-Chief of Hospital of Special Surgery Spine and an Attending Orthopedic Surgeon at HSS, shared his vision of the future of the Spine Market with ... (read more)

Click the button below to download and read the complete "SMISS 2024 - MIS Spine Continues to Grow" perspective article by Erin Dorgan, SmartTRAK Sr Analyst, Spine and Orthobiologics.

Topics: Spine
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2 min read

Trends and Developments in Spine Enabling Technologies at NASS 2024

By Thomas Wallick on 9/24/24 9:36 AM

SmartTRAK is attending the upcoming North American Spine Society (NASS) meeting being held Sept. 25-28 in Chicago, Our team can't wait to see all of our colleagues at the premier meeting for the spine market. To help you get ready for the meeting, in the following video, Elise Wolf, SmartTRAK's VP & GM of Orthopedics and Digital, reviews the latest trends and developments in the Spine Enabling Technologies market.



If you would like to see more of what SmartTRAK has to offer in spine coverage, including some of our recent articles on the trends and developments in the Spine Enabling Technologies market, or if you would like to meet with us at NASS 2024 in Chicago,  just click the button below.

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2 min read

NASS 2024: Bone Replacement Developments to Know Before You Go

By Thomas Wallick on 9/23/24 1:35 PM

SmartTRAK is attending the upcoming North American Spine Society (NASS) meeting being held Sept. 25-28 in Chicago, and we can't wait to see all of our colleagues at the premier meeting for the spine market. To help you get ready for the meeting, Erin Dorgan, SmartTRAK Senior Analyst, Spine, has recorded this video update with an overview of the bone replacement products and companies to watch at NASS 2024.



If you would like to see more of what SmartTRAK has to offer in spine coverage and the bone replacement market, including some of our recent articles, or meet with us at NASS 2024,  just click the button below.

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2 min read

NASS 2024: What to Know Before You Go

By Thomas Wallick on 9/17/24 9:35 AM

SmartTRAK is attending the upcoming North American Spine Society (NASS) meeting being held Sept. 25-28 in Chicago, and we can't wait to see all of our colleagues at the premier meeting for the spine market. To help you get ready for the meeting, Erin Dorgan, SmartTRAK Senior Analyst, Spine, has recorded a video update with the trends, key players and innovations to know before the show.



If you would like to see more of what SmartTRAK has to offer in spine market coverage, including some of our recent articles, or meet with us at NASS 2024,  just click the button below.

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