<img height="1" width="1" style="display:none" src="https://www.facebook.com/tr?id=1000083763474443&amp;ev=PageView&amp;noscript=1">
Log In

SmartTRAK Life Sciences News and Analysis Blog

3 min read

Medical Care for NFL Teams: Standards and Initiatives from AOSSM 2025

By David Shepard on 8/5/25 9:30 AM

James Voos, MD, chair of the Department of Orthopedics and Sports Medicine at University Hospitals Cleveland Medical Center, Cleveland Browns team physician, and president of the NFL Physicians Society (NFLPS), shares his goals for the society and offers insight into how he is using biotechnology to monitor recovery, prevent further injuries, and safely return athletes to competition.

James Voos, MD, president of the NFL Physicians Society (NFLPS), discusses the society's efforts to standardize care for NFL players across the league in an interview with SmartTRAK at the American Orthopaedic Society for Sports Medicine (AOSSM) 2025 Annual Meeting recently held in Nashville, TN.

Dr. Voos also shares an update on ongoing clinical research for osteoarthritis treatment with stem cells. To listen to the interview, please click on the following video (4:18 minutes). A link to download a complete transcript of the interview is alsoprovided below. 

 

SmartTRAK: Hi, this is Dave Shepard. I'm here at the AOSSM 2025. Keep watching for my interview with Dr. James Voos, who is the team physician for the Cleveland Browns, and also the president of the NFL Physicians’ Society. Dr. Voos, thanks for joining us.

James Voos, MD:
 Thank you very much for the invitation. I appreciate it.

Excellent. Tell me a little bit about the NFL PS and a little bit about what you're doing, what your initiatives are, what your goals are.

JV: 
As president of the NFL Physician Society, we represent all of the physicians that provide care for our professional athletes in football. That's not only our orthopedic surgeons, but our medical physicians and all of our associated consultants. So we help to provide standards for how to practice across the league, and that way we assure that every athlete and every team has ...

Interested in how biotechnology can be used to monitor recovery, prevent further injuries and safely return athletes to competition? Click
the button below to download the full transcript of SmartTRAK GM/Sr Analyst David Shepard's interview of James Voos, MD, president of the NFL Physicians Society (NFLPS) from AOSSM 2025. Get the Transcript

Continue Reading
2 min read

CMS Proposes Major Changes to Skin Substitutes Reimbursement: What You Need to Know

By Kris Flinn on 7/28/25 5:33 PM



SmartTRAK's industry experts discuss CMS’ proposed changes to skin substitutes reimbursement and their potential effects on wound care practices.

On Monday, July 14, the Centers for Medicare & Medicaid Services (CMS) released new proposals for the reimbursement of Skin Substitutes in the physician fee schedule sites of care. SmartTRAK estimates the 2024 US Skin Substitutes Market at almost $8B, with over three-quarters of that amount coming from the Physician Office and Mobile+ sites of care.

In the following video, SmartTRAK Wound General Manager Kris Flinn is joined by Senior Analysts Jay Merkel and Elizabeth Anderson to explain the CMS proposals and explore their potential impacts on US wound care (17:33 min). To listen to the discussion, click the video below. A link to download a full transcript of the discussion is also provided below. 

 

SmartTRAK is pleased to announce the availability of its recent report, “Addressable Market Projection: Skin Substitutes,” which delivers in-depth data and forecasting for the rapidly evolving Advanced Wound Care (AWC) market. For info on how to access it, click the button below.Get the Analysis

Continue Reading
2 min read

Skin Substitutes Get WISeR – Will it Impact the Market?

By Jay Merkel on 7/22/25 10:44 AM

SmartTRAK reviews CMS’ new WISeR model and its potential impact on the US Skin Substitutes Market.

 A new initiative launched by the Centers for Medicare & Medicaid Services (CMS)’s Innovation Center, which develops payment and service delivery model pilot programs, could impact the Skin Substitutes Market in several states in 2026 and beyond. Other models to come out of the Innovation Center are: Comprehensive Care of Joint Replacement Model and the Maryland Total Cost of Care Model. The newest model, the WISeR Model, short for Wasteful and Inappropriate Service Reduction, leverages AI technology along with human clinical review to streamline prior authorization processes for certain product categories.
 
The WISer Model hopes to use technology to root out wasteful services with limited clinical evidence of effectiveness. It targets many different product categories that CMS determined have a higher risk of waste, fraud and abuse. One such category is skin and tissue substitutes.
 

In this comprehensive article, SmartTRAK provides an overview of the WISeR Model and its potential market impact on skin substitutes.

Click the button below to download and read the complete article "Skin Substitutes Get WISeR – Will it Impact the Market?" by Jay Merkel, SmartTRAK Sr Analyst, Wound.Get the Article

Continue Reading
2 min read

Deals in Advanced Wound Care

By Susan Paquette on 7/1/25 9:30 AM

Nearly half a billion in US dollars has been invested in Advanced Wound Care over the last 18 months. Learn where the money is going.

Over the past three years the global Advanced Wound Care Market has almost doubled, an exciting market for investment according to SmartTRAK estimates. The biggest deal in Advanced Wound Care (AWC) has been Coloplast's acquisition of Kerecis in 2023. Kerecis, a startup in the US Skin Substitute Market, demonstrated strong growth and the potential to have a global presence, justifying the high price. Startups have been a key component of the market, with new technologies and products over the years, and have been advancing their portfolios through IPOs, strategic partnerships, and investments. 

This downloadable article reviews the recent top deals and investment trends in AWC, including:

  • Recent Global Wound Care Investments
    • Top Deals and Investments Jan 2024 through June 2025
  • Market Trends
    • Although the US Skin Substitute/ CAMPs Market has seen exponential growth in the last few years, that isn't where global investment is occurring.
  • Investment by Geography
    • US and Canada Wound Care Investments
    • UK, Europe, and Rest of World (ROW)
  • Early-Stage Investments
    • Non-Dilutive Funding Sources
    • Strategic and Insurance Provider Investments

Want to know which deals are shaping the future of wound care? Click below to download the full article, “Deals in Advanced Wound Care,” co-authored by Dr. Mitchell C. Sanders, CEO, ProDevLabs and Susan Paquette, SmartTRAK Senior Advisor, Wound, to get a firsthand look at the key investment trends driving this dynamic market.

Get the Article

Topics: Wound Care
Continue Reading
2 min read

Insights Involving Real-World Evidence and Wound Care

By Elizabeth Anderson on 6/12/25 10:33 AM

Caroline Fife, MD, CMO of Intellicure and Executive Director of the US Wound Registry, discusses real-world evidence in wound care and other topics in an interview with SmartTRAK. 

Caroline Fife, MD, discusses insights from the Intellicure database about what diabetic foot ulcer (DFU) and venous leg ulcer (VLU) patients look like, the role of real-world evidence in wound care and the challenges in treating wound care patients.

To find out more, including the challenges for manufacturers and the systemic issues in wound care and payment policies, click on the following video to listen to the interview (37:48 min). A link to download the complete transcript of the interview is provided below. Interview topics by timecode are also provided below. 

 

Interview Outline by Timecode: 

00:30 Overlap between diabetic foot ulcers and venous leg ulcers.
08:19 Challenges in wound classification and diagnosis.
14:02 Limitations of randomized controlled trials and the role of real-world evidence.
17:38 Potential for biomarkers and intermediate outcome measures.
21:57 Neglected wound types and nutritional deficiencies.
29:14 Barriers to wound care implementation.
32:50 Opportunities for change in wound care practices.
34:31 Local coverage determinations (LCDs) and manufacturer challenges.
35:16 Systemic issues in wound care and payment policies.

Click the button below to download and read the complete transcript of SmartTRAK's interview with Caroline Fife, MD, CMO of Intellicure, conducted by  Elizabeth Anderson, SmartTRAK Senior Analyst, Wound Biologics.Get the Transcript

Continue Reading
3 min read

Is Nitric Oxide the Next Big Thing in Wound Care?

By Susan Paquette on 6/9/25 9:56 AM

Nitric Oxide (NO) has numerous benefits for wound healing but has challenges associated with its delivery. Several companies are addressing those challenges and creating an exciting opportunity in wound care.

Nitric oxide (NO) was named “Molecule of the Year” by the journal Science in 1992, and six years later, three US scientists were awarded the Nobel Prize for Physiology and Medicine for their efforts to prove that NO, an endogenous gas and free radical, could have crucial biological effects. One of the well-known medical uses of NO is via nitroglycerin, a precursor to NO, to prevent and treat chest pain (angina). It works by relaxing blood vessels, which decreases the amount of work the heart has to do. NO has been identified for its value in chronic wound healing for many years because of its function in vasodilation, relaxing blood vessels and increasing blood flow, as well as its broad-spectrum antimicrobial and antibiofilm activity.

No products have yet reached the market for chronic wounds; however, SmartTRAK has noted increasing activity related to the benefits of NO for wound healing. In fact, an article was published earlier this year entitled “Emerging Strategies for Nitric Oxide Production and Their Topical Application as Nano Dressings to Promote Diabetic Wound Healing.” The article identified four primary modes in which NO benefits the diabetic wound healing process: providing antimicrobial properties, promoting angiogenesis, regulating inflammation and promoting tissue regeneration and remodeling.

This market outlook article will discuss in detail the following subjects:

Topics: Wound Care
Continue Reading
2 min read

Impact of LCD Postponement on the US Skin Substitutes Market

By Kris Flinn on 4/21/25 3:55 PM

Wound GM Kris Flinn and Senior Analysts Elizabeth Anderson and Jay Merkel discuss the impact of delay and how industry players may choose to react.

On April 11, 2025, Centers for Medicare and Medicaid Services announced that the Treatment of Diabetic Foot Ulcers and Venous Leg Ulcers Final Local Coverage Determinations (LCDs) effective date will be delayed until January 1, 2026. In this video (16:43 minutes), SmartTRAK Wound GM Kris Flinn and Senior Analysts Elizabeth Anderson and Jay Merkel discuss the impact of delay, and how industry players may choose to react.

 

The SmartTRAK Wound Team will be in attendance at the upcoming SAWC Spring conference in Grapevine, TX (April 30 to May 4). Please register here to meet the team.Meet The Team

Continue Reading
2 min read

LCD Uncertainty Bringing Disruption to CAMPs

By Susan Paquette on 3/25/25 9:45 AM

CAMPs 2025 meeting highlights the use of CAMPs in all sites of care.

SmartTRAK reports the latest news and trends in cellular, acellular and matrix-like products (CAMPs) from the CAMPs 2025 Wound Care Summit held February 28 to March 2 in Fort Lauderdale, Florida. Hosted by the Journal of Wound Care (JWC), CAMPs 2025 showcased new clinical research, consensus guidelines and presentations supporting the use of CAMPs amid uncertainties in reimbursement for these products in the US Market for Skin Substitutes.

The subjects discussed in this downloadable SmartTRAK Perspective article include:

  • The Broad Use of CAMPs
    • Sessions at CAMPs 2025 supported the broad use of CAMPs, including applications for diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs) as well as those for limb salvage, acute care, tunneling wounds, Mohs surgery, trauma, burns and pressure ulcers (PrUs). SmartTRAK expects the use of CAMPs to ... (read more)
  • LCD Discussions Taking Center Stage
    • With the implementation of the MAC LCDs delayed until April 13th, a prevailing question among attendees at the conference was whether the LCDs would actually be implemented or further delayed. SmartTRAK spoke with clinicians and industry representatives to obtain their views on the LCDs and ... (read more)
  • Market Disruption – 2025 Earnings Projections
    • For public companies providing skin substitutes to the market, uncertainty was a major theme in their 2025 guidance SmartTRAK  summarizes comments from companies that mentioned the LCD in their 2025 revenue projections ... (read more)

Although a significant amount of discussion with clinicians and industry focused on revising the reimbursement methodology for skin substitutes, companies are still moving forward with clinical studies. SmartTRAK is currently tracking 26 clinical trials for DFUs and VLUs, as mentioned earlier and ...

To find out more about news and trends from CAMPs 2025, just click the button below to download the complete market perspective article "LCD Uncertainty Bringing Disruption to CAMPs" by Susan Paquette, VP & General Manager, Wound.


SmartTRAK is the Medtech industry’s only global Insights-as-a-Service solution for the Orthopedics, Wound Care, Regenerative Medicine and Neuro Therapy markets. SmartTRAK’s propriety methodology turns disparate data from hundreds of sources into powerful insights customers can rely on as the trusted source for strategic decision-making. The SmartTRAK enterprise platform includes rich daily updates, comprehensive market coverage and simple-to-use tools and dashboards for market, product and financial analysis. Customers leveraging the SmartTRAK platform also have direct access to market experts for inquiries and advisory services. If you would like a demo of what SmartTRAK has to offer and see how we can help increase proficiency, improve productivity and reduce costs for your company, just click here.

Topics: Wound Care
Continue Reading
3 min read

Artificial Intelligence in Wound Diagnostics: Four Companies to Watch in 2025

By Kris Flinn on 3/25/25 9:30 AM

SmartTRAK highlights four wound diagnostics companies utilizing artificial intelligence to watch in 2025.

Artificial intelligence (AI) is becoming increasingly ubiquitous in our personal and professional lives. AI is already being applied in healthcare in areas such as image analysis, personalized treatments and predictive care. Future potential applications include improved analysis of healthcare data, optimizing medication doses and enhancing patient education. The challenges of AI are also widely discussed, with ethical and legal concerns combined with a general worry that patient care could become dehumanized and distanced from healthcare professionals.

In this downloadable article, SmartTRAK identifies and discusses the following four diagnostic companies facilitating AI that should be watched in 2025:

  • eKare
    • Wound assessment company eKare has been at the forefront of the conversation around AI in wound care. The core functionality of inSight, a 3D digital wound imaging system, includes AI aspects such as ... (read more)
  • Mimosa Diagnostics
    • Canadian tissue oximetry company Mimosa Diagnostics primarily implements AI to enhance the usability of its Mimosa Pro device, which uses ... (read more)
  • Spectral AI
    • Texas-based Spectral AI has undertaken significant fundraising over recent years. Over $150 million of Biomedical Advanced Research and Development Authority (BARDA) funding since 2013 has facilitated ... (read more)
  • Swift Medical
    • Toronto-based Swift Medical saw a significant change in 2024. New leadership was announced in June as Dwayne Sansone and Stratos Davlos assumed the roles of CEO and CTO, respectively. The company received ... (read more)

The benefits of AI in wound care include accuracy and efficiency of wound characterization, remote monitoring, personalized care and increased accessibility to wound care ...

To find out more about how these companies are incorporating AI, just click the button below to download the complete market outlook article "Artificial Intelligence in Wound Diagnostics: Four Companies to Watch in 2025" by Kris Flinn, SmartTRAK General Manager, Wound.Get the Article

Continue Reading
2 min read

Feel the Pressure: Compression Trends for 2025

By Jay Merkel on 2/19/25 9:33 AM

SmartTRAK highlights the key trends in the US Compression Therapy market that will drive growth over the next few years.

In the US Market for Compression Devices, SmartTRAK projects revenues to reach a 5-year CAGR of +6.2%. In 2025, SmartTRAK expects mid-single-digit growth to continue and sees three key trends that will help drive growth over the next several years. These include:

  • Expanding Reimbursement for Lymphedema Products 
    • One of the biggest growth drivers for compression therapies in 2025 is expanding reimbursement for the treatment of lymphedema. With more than three million lymphedema patients estimated in the US alone, SmartTRAK expects ... (read more)
  • Improving Ease of Use for Compression Garments
    • SmartTRAK expects several companies to develop or refine compression garments in the years ahead with a focus on improving ease of use. With the growing number of patients having access to compression garments day and night, it’s become even more important for ... (read more)
  • Dynamic Compression Innovations Improving Portability
    • In the world of dynamic compression, portability is the name of the game and SmartTRAK expects to see ... (read more)

Want to stay ahead of the curve in the US compression device market for 2025 and beyond? Industry trends, regulatory changes and new reimbursement codes are shaping the future—are you prepared?

Click the button below to download Jay Merkel’s market outlook article, "Feel the Pressure: Compression Trends for 2025." As SmartTRAK’s senior analyst, Wound, Jay provides an informative analysis of the latest market shifts, including new compression codes and major code revisions set to take effect on April 1, 2025.

Get the Article

Topics: Wound Care
Continue Reading
  • There are no suggestions because the search field is empty.

Recent Articles